The H(abc) Domain of the SNARE Vam3 Interacts with the HOPS Tethering Complex to Facilitate Vacuole Fusion

Membrane fusion at vacuoles requires a consecutive action of the HOPS tethering complex, which is recruited by the Rab GTPase Ypt7, and vacuolar SNAREs to drive membrane fusion. It is assumed that the Sec1/Munc18-like Vps33 within the HOPS complex is largely responsible for SNARE chaperoning. Here,...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Lürick, Anna, Kuhlee, Anne, Bröcker, Cornelia, Kümmel, Daniel, Raunser, Stefan, Ungermann, Christian
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2015
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342457/
https://ncbi.nlm.nih.gov/pubmed/25564619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.631465
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