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Vam7p, a vacuolar SNAP-25 homolog, is required for SNARE complex integrity and vacuole docking and fusion.

The vacuole v-t-SNARE complex is disassembled by Sec17p/alpha-SNAP and Sec18p/NSF prior to vacuole docking and fusion. We now report a functional characterization of the vacuolar SNARE Vam7p, a SNAP-25 homolog. Although Vam7p has no hydrophobic domains, it is tightly associated with the vacuolar mem...

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Bibliographic Details
Main Authors: Ungermann, C, Wickner, W
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170665/
https://ncbi.nlm.nih.gov/pubmed/9628864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.12.3269
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