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Multivalent Rab interactions determine tether-mediated membrane fusion
Membrane fusion at endomembranes requires cross-talk between Rab GTPases and tethers to drive SNARE-mediated lipid bilayer mixing. Several tethers have multiple Rab-binding sites with largely untested function. Here we dissected the lysosomal HOPS complex as a tethering complex with just two binding...
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| Publicado no: | Mol Biol Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5231900/ https://ncbi.nlm.nih.gov/pubmed/27852901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-11-0764 |
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