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Molecular architecture of the multisubunit homotypic fusion and vacuole protein sorting (HOPS) tethering complex

Membrane fusion within the eukaryotic endomembrane system depends on the initial recognition of Rab GTPase on transport vesicles by multisubunit tethering complexes and subsequent coupling to SNARE-mediated fusion. The conserved vacuolar/lysosomal homotypic fusion and vacuole protein sorting (HOPS)...

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Detalhes bibliográficos
Main Authors: Bröcker, Cornelia, Kuhlee, Anne, Gatsogiannis, Christos, kleine Balderhaar, Henning J., Hönscher, Carina, Engelbrecht-Vandré, Siegfried, Ungermann, Christian, Raunser, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277535/
https://ncbi.nlm.nih.gov/pubmed/22308417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117797109
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