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Structural Identification of the Vps18 β-Propeller Reveals a Critical Role in the HOPS Complex Stability and Function
Membrane fusion at the vacuole, the lysosome equivalent in yeast, requires the HOPS tethering complex, which is recruited by the Rab7 GTPase Ypt7. HOPS provides a template for the assembly of SNAREs and thus likely confers fusion at a distinct position on vacuoles. Five of the six subunits in HOPS h...
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| Izdano u: | J Biol Chem |
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| Glavni autori: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246104/ https://ncbi.nlm.nih.gov/pubmed/25324549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.602714 |
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