HDAC5 controls MEF2C-driven sclerostin expression in osteocytes

Osteocytes secrete paracrine factors that regulate the balance between bone formation and destruction. Among these molecules, sclerostin (encoded by the gene SOST) inhibits osteoblastic bone formation, and is an osteoporosis drug target. The molecular mechanisms underlying SOST expression remain lar...

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Detaylı Bibliyografya
Yayımlandı:J Bone Miner Res
Asıl Yazarlar: Wein, Marc N., Spatz, Jordan, Nishimori, Shigeki, Doench, John, Root, David, Babij, Philip, Nagano, Kenichi, Baron, Roland, Brooks, Daniel, Bouxsein, Mary, Pajevic, Paola Divieti, Kronenberg, Henry M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342334/
https://ncbi.nlm.nih.gov/pubmed/25271055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2381
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