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Insights into Human β-Cardiac Myosin Function from Single Molecule and Single Cell Studies
β-Cardiac myosin is a mechanoenzyme that converts the energy from ATP hydrolysis into a mechanical force that drives contractility in muscle. Thirty percent of the point mutations that result in hypertrophic cardiomyopathy are localized to MYH7, the gene encoding human β-cardiac myosin heavy chain (...
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| Publicado no: | J Cardiovasc Transl Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4342148/ https://ncbi.nlm.nih.gov/pubmed/20560001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-009-9129-2 |
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