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Insights into Human β-Cardiac Myosin Function from Single Molecule and Single Cell Studies

β-Cardiac myosin is a mechanoenzyme that converts the energy from ATP hydrolysis into a mechanical force that drives contractility in muscle. Thirty percent of the point mutations that result in hypertrophic cardiomyopathy are localized to MYH7, the gene encoding human β-cardiac myosin heavy chain (...

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Podrobná bibliografie
Vydáno v:J Cardiovasc Transl Res
Hlavní autoři: Sivaramakrishnan, Sivaraj, Ashley, Euan, Leinwand, Leslie, Spudich, James A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342148/
https://ncbi.nlm.nih.gov/pubmed/20560001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12265-009-9129-2
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