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Absorption of Ester Prodrugs in Caco-2 and Rat Intestine Models
The aim of this study was to elucidate the absorption mechanism in Caco-2 and rat intestine models in order to improve the accuracy of prediction of oral absorption of ester prodrugs. Pivampicillin and cefcapene pivoxil hydrochloride (CFPN-PI), ester-type oral antibiotics, were chosen as model ester...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC434205/ https://ncbi.nlm.nih.gov/pubmed/15215116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.7.2604-2609.2004 |
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