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Intestinal absorption and biliary elimination of glycyrrhizic acid diethyl ester in rats

BACKGROUND: The purpose of this study was to evaluate absorption and elimination from the gastrointestinal tract of glycyrrhizic acid diethyl ester (GZ-DE) which was prepared as a prodrug of glycyrrhizic acid (a poorly absorbed compound) in rats. METHODS: After the GZ-DE solution was administered vi...

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Main Authors: Koga, Kenjiro, Kawamura, Mayuri, Iwase, Hiroshi, Yoshikawa, Nobuji
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808209/
https://ncbi.nlm.nih.gov/pubmed/24174868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S51638
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