Applying polygenic risk scores to postpartum depression

OBJECTIVE: The etiology of major depressive disorder (MDD) is likely to be heterogeneous, but postpartum depression (PPD) is hypothesized to represent a more homogenous subset of MDD. We use genome-wide SNP data to explore this hypothesis. METHOD: We assembled a total cohort of 1,420 self-report cas...

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Pubblicato in:Arch Womens Ment Health
Autori principali: Byrne, Enda M, Carrillo-Roa, Tania, Meltzer-Brody, Samantha, Penninx, Brenda WJH, Sallis, Hannah M, Viktorin, Alexander, Chapman, Brett, Henders, Anjali K, Pergadia, Michele L, Heath, Andrew C, Madden, Pamela AF, Sullivan, Patrick F., Boschloo, Lynn, van Grootheest, Gerard, McMahon, George, Lawlor, Debbie A, Landén, Mikael, Lichtenstein, Paul, Magnusson, Patrik KE, Evans, David M, Montgomery, Grant W, Boomsma, Dorret I, Martin, Nicholas G, Wray, Naomi R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4341990/
https://ncbi.nlm.nih.gov/pubmed/25037970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00737-014-0428-5
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