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Effect of polygenic risk scores on depression in childhood trauma

Background Research on gene × environment interaction in major depressive disorder (MDD) has thus far primarily focused on candidate genes, although genetic effects are known to be polygenic. Aims To test whether the effect of polygenic risk scores on MDD is moderated by childhood trauma. Method The...

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Hlavní autoři: Peyrot, Wouter J., Milaneschi, Yuri, Abdellaoui, Abdel, Sullivan, Patrick F., Hottenga, Jouke J., Boomsma, Dorret I., Penninx, Brenda W. J. H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal College of Psychiatrists 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4118052/
https://ncbi.nlm.nih.gov/pubmed/24925986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1192/bjp.bp.113.143081
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