Polygenic dissection of major depression clinical heterogeneity

The molecular mechanisms underlying Major Depressive Disorder (MDD) are largely unknown. Limited success of previous genetics studies may be attributable to heterogeneity of MDD, aggregating biologically different subtypes. We examined the polygenic features of MDD and two common clinical subtypes (...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Milaneschi, Yuri, Lamers, Femke, Peyrot, Wouter J, Abdellaoui, Abdel, Willemsen, Gonneke, Hottenga, Jouke-Jan, Jansen, Rick, Mbarek, Hamdi, Dehghan, Abbas, Lu, Chen, Boomsma, Dorret I, Penninx, Brenda WJH
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546325/
https://ncbi.nlm.nih.gov/pubmed/26122587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.86
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