Polygenic dissection of major depression clinical heterogeneity

The molecular mechanisms underlying Major Depressive Disorder (MDD) are largely unknown. Limited success of previous genetics studies may be attributable to heterogeneity of MDD, aggregating biologically different subtypes. We examined the polygenic features of MDD and two common clinical subtypes (...

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Pubblicato in:Mol Psychiatry
Autori principali: Milaneschi, Yuri, Lamers, Femke, Peyrot, Wouter J, Abdellaoui, Abdel, Willemsen, Gonneke, Hottenga, Jouke-Jan, Jansen, Rick, Mbarek, Hamdi, Dehghan, Abbas, Lu, Chen, Boomsma, Dorret I, Penninx, Brenda WJH
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546325/
https://ncbi.nlm.nih.gov/pubmed/26122587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.86
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