Dihydropteroate Synthase Mutations in Pneumocystis jiroveci Can Affect Sulfamethoxazole Resistance in a Saccharomyces cerevisiae Model

Dihydropteroate synthase (DHPS) mutations in Pneumocystis jiroveci have been associated epidemiologically with resistance to sulfamethoxazole (SMX). Since P. jiroveci cannot be cultured, inherent drug resistance cannot be measured. This study explores the effects of these mutations in a tractable mo...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Iliades, Peter, Meshnick, Steven R., Macreadie, Ian G.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2004
Matèries:	Mechanisms of Resistance
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434176/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15215118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.7.2617-2623.2004
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