Recapitulation in Saccharomyces cerevisiae of Cytochrome b Mutations Conferring Resistance to Atovaquone in Pneumocystis jiroveci

Pneumocystis jiroveci (human-derived P. carinii) is an opportunistic pathogenic fungus which causes pneumonia and is life-threatening in immunocompromised individuals. Spontaneously acquired resistance to atovaquone, a hydroxynaphthoquinone that is used to treat P. jiroveci infections, was linked to...

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Bibliografski detalji
Glavni autori: Hill, Philip, Kessl, Jacques, Fisher, Nicholas, Meshnick, Steven, Trumpower, Bernard L., Meunier, Brigitte
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Mechanisms of Resistance
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC182622/
https://ncbi.nlm.nih.gov/pubmed/12936966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.9.2725-2731.2003
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