Recapitulation in Saccharomyces cerevisiae of Cytochrome b Mutations Conferring Resistance to Atovaquone in Pneumocystis jiroveci

Pneumocystis jiroveci (human-derived P. carinii) is an opportunistic pathogenic fungus which causes pneumonia and is life-threatening in immunocompromised individuals. Spontaneously acquired resistance to atovaquone, a hydroxynaphthoquinone that is used to treat P. jiroveci infections, was linked to...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Hill, Philip, Kessl, Jacques, Fisher, Nicholas, Meshnick, Steven, Trumpower, Bernard L., Meunier, Brigitte
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC182622/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12936966/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.9.2725-2731.2003
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