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Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo.

We describe studies of gene transfer and expression of the human glucocerebrosidase cDNA by a Moloney murine leukemia virus (MoMuLV)-based retroviral vector in a murine gene transfer/bone marrow transplant (BMT) model. Pluripotent hematopoietic stem cells (HSCs) were assayed as the colony-forming un...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Challita, P M, Kohn, D B
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1994
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC43410/
https://ncbi.nlm.nih.gov/pubmed/8146155
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