Transmitted Human Immunodeficiency Virus Type 1 Carrying the D67N or K219Q/E Mutation Evolves Rapidly to Zidovudine Resistance In Vitro and Shows a High Replicative Fitness in the Presence of Zidovudine

Drug-naive patients infected with drug-resistant human immunodeficiency virus type 1 (HIV-1) who initiate antiretroviral therapy show a shorter time to virologic failure than patients infected with wild-type (WT) viruses. Resistance-related HIV genotypes not commonly seen in treated patients, which...

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Detalhes bibliográficos
Main Authors: García-Lerma, J. Gerardo, MacInnes, Hamish, Bennett, Diane, Weinstock, Hillard, Heneine, Walid
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC434071/
https://ncbi.nlm.nih.gov/pubmed/15220429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.14.7545-7552.2004
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