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The Fitness Cost of Mutations Associated with Human Immunodeficiency Virus Type 1 Drug Resistance Is Modulated by Mutational Interactions

It is generally accepted that the fitness cost of resistance mutations plays a role in the persistence of transmitted drug-resistant human immunodeficiency virus type 1 and that mutations that confer a high fitness cost are less able to persist in the absence of drug pressure. Here, we show that the...

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Hlavní autoři: Cong, Mian-er, Heneine, Walid, García-Lerma, J. Gerardo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865994/
https://ncbi.nlm.nih.gov/pubmed/17192300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02712-06
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