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HIV, transmitted drug resistance, and the paradox of preexposure prophylaxis

The administration of antiretrovirals before HIV exposure to prevent infection (i.e., preexposure prophylaxis; PrEP) is under evaluation in clinical trials. Because PrEP is based on antiretrovirals, there is considerable concern that it could substantially increase transmitted resistance, particular...

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Detalhes bibliográficos
Main Authors: Supervie, Virginie, García-Lerma, J. Gerardo, Heneine, Walid, Blower, Sally
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901470/
https://ncbi.nlm.nih.gov/pubmed/20616092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006061107
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