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Identification of signaling pathways related to drug efficacy in hepatocellular carcinoma via integration of phosphoproteomic, genomic and clinical data

Hepatocellular Carcinoma (HCC) is one of the leading causes of death worldwide, with only a handful of treatments effective in unresectable HCC. Most of the clinical trials for HCC using new generation interventions (drug-targeted therapies) have poor efficacy whereas just a few of them show some pr...

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Bibliografiske detaljer
Udgivet i:Proc IEEE Int Symp Bioinformatics Bioeng
Main Authors: Melas, Ioannis N., Lauffenburger, Douglas A., Alexopoulos, Leonidas G.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340693/
https://ncbi.nlm.nih.gov/pubmed/25729777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/BIBE.2013.6701683
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