Targeted depletion of a MDSC subset unmasks pancreatic ductal adenocarcinoma to adaptive immunity

OBJECTIVE: Pancreatic ductal adenocarcinoma (PDA) is characterized by a robust desmoplasia, including the notable accumulation of immunosuppressive cells that shield neoplastic cells from immune detection. Immune evasion may be further enhanced if the malignant cells fail to express high levels of a...

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Publicat a:Gut
Autors principals: Stromnes, Ingunn M., Brockenbrough, Scott, Izeradjene, Kamel, Carlson, Markus A., Cuevas, Carlos, Simmons, Randi M., Greenberg, Philip D., Hingorani, Sunil R.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340484/
https://ncbi.nlm.nih.gov/pubmed/24555999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-306271
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