Targeted depletion of a MDSC subset unmasks pancreatic ductal adenocarcinoma to adaptive immunity

OBJECTIVE: Pancreatic ductal adenocarcinoma (PDA) is characterized by a robust desmoplasia, including the notable accumulation of immunosuppressive cells that shield neoplastic cells from immune detection. Immune evasion may be further enhanced if the malignant cells fail to express high levels of a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Gut
Prif Awduron: Stromnes, Ingunn M., Brockenbrough, Scott, Izeradjene, Kamel, Carlson, Markus A., Cuevas, Carlos, Simmons, Randi M., Greenberg, Philip D., Hingorani, Sunil R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340484/
https://ncbi.nlm.nih.gov/pubmed/24555999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-306271
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