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Functional Analysis of the Putative Integrin Recognition Motif on Adeno-associated Virus 9

Adeno-associated viruses (AAVs) display a highly conserved NGR motif on the capsid surface. Earlier studies have established this tripeptide motif as being essential for integrin-mediated uptake of recombinant AAV serotype 2 (AAV2) in cultured cells. However, functional attributes of this putative i...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Shen, Shen, Berry, Garrett E., Castellanos Rivera, Ruth M., Cheung, Roland Y., Troupes, Andrew N., Brown, Sarah M., Kafri, Tal, Asokan, Aravind
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340397/
https://ncbi.nlm.nih.gov/pubmed/25404742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.608281
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