Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity

Autophagy is a catabolic process involved in maintaining energy and organelle homeostasis. The relationship between obesity and the regulation of autophagy is cell type specific. Despite adverse consequences of obesity on cardiac structure and function, the contribution of altered cardiac autophagy...

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Bibliografische gegevens
Gepubliceerd in:J Lipid Res
Hoofdauteurs: Jaishy, Bharat, Zhang, Quanjiang, Chung, Heaseung S., Riehle, Christian, Soto, Jamie, Jenkins, Stephen, Abel, Patrick, Cowart, L. Ashley, Van Eyk, Jennifer E., Abel, E. Dale
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2015
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340303/
https://ncbi.nlm.nih.gov/pubmed/25529920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M055152
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