Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity

Autophagy is a catabolic process involved in maintaining energy and organelle homeostasis. The relationship between obesity and the regulation of autophagy is cell type specific. Despite adverse consequences of obesity on cardiac structure and function, the contribution of altered cardiac autophagy...

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Bibliografske podrobnosti
izdano v:J Lipid Res
Main Authors: Jaishy, Bharat, Zhang, Quanjiang, Chung, Heaseung S., Riehle, Christian, Soto, Jamie, Jenkins, Stephen, Abel, Patrick, Cowart, L. Ashley, Van Eyk, Jennifer E., Abel, E. Dale
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2015
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340303/
https://ncbi.nlm.nih.gov/pubmed/25529920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M055152
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