Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity

Autophagy is a catabolic process involved in maintaining energy and organelle homeostasis. The relationship between obesity and the regulation of autophagy is cell type specific. Despite adverse consequences of obesity on cardiac structure and function, the contribution of altered cardiac autophagy...

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發表在:J Lipid Res
Main Authors: Jaishy, Bharat, Zhang, Quanjiang, Chung, Heaseung S., Riehle, Christian, Soto, Jamie, Jenkins, Stephen, Abel, Patrick, Cowart, L. Ashley, Van Eyk, Jennifer E., Abel, E. Dale
格式: Artigo
語言:Inglês
出版: The American Society for Biochemistry and Molecular Biology 2015
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340303/
https://ncbi.nlm.nih.gov/pubmed/25529920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M055152
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