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Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

Non-homologous end joining (NHEJ) is a major pathway to repair DNA double-strand breaks (DSBs), which can display different types of broken ends. However, it is unclear how NHEJ factors organize to repair diverse types of DNA breaks. Here, through systematic analysis of the human NHEJ factor interac...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Xing, Mengtan, Yang, Mingrui, Huo, Wei, Feng, Feng, Wei, Leizhen, Jiang, Wenxia, Ning, Shaokai, Yan, Zhenxin, Li, Wen, Wang, Qingsong, Hou, Mei, Dong, Chunxia, Guo, Rong, Gao, Ge, Ji, Jianguo, Zha, Shan, Lan, Li, Liang, Huanhuan, Xu, Dongyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339890/
https://ncbi.nlm.nih.gov/pubmed/25670504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7233
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