Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs

The human artificial chromosome (HAC) vector is a promising tool to improve the problematic suppression and position effects of transgene expression frequently seen in transgenic cells and animals produced by conventional plasmid or viral vectors. We generated transgenic mice maintaining a single HA...

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Detalhes bibliográficos
Publicado no:Chromosoma
Main Authors: Hasegawa, Yoshinori, Ishikura, Tomoyuki, Hasegawa, Takanori, Watanabe, Takashi, Suzuki, Junpei, Nakayama, Manabu, Okamura, Yoshiaki, Okazaki, Tuneko, Koseki, Haruhiko, Ohara, Osamu, Ikeno, Masashi, Masumoto, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339693/
https://ncbi.nlm.nih.gov/pubmed/25308419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00412-014-0488-3
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