Loading...
SILENCING GASTRIN-RELEASING PEPTIDE RECEPTOR SUPPRESSES KEY REGULATORS OF AEROBIC GLYCOLYSIS IN NEUROBLASTOMA CELLS
BACKGROUND: Under normoxic conditions, cancer cells use aerobic glycolysis as opposed to glucose oxidation for energy production; this altered metabolism correlates with poor outcomes in neuroblastoma. Hypoxia-inducible factor-1α (HIF-1α) and pyruvate dehydrogenase kinase 4 (PDK4) regulate aerobic g...
Saved in:
| Published in: | Pediatr Blood Cancer |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4339541/ https://ncbi.nlm.nih.gov/pubmed/25630799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.25348 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|