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Naturally occurring polyphenol, morin hydrate, inhibits enzymatic activity of N-methylpurine DNA glycosylase, a DNA repair enzyme with various roles in human disease

Interest in the mechanisms of DNA repair pathways, including the base excision repair (BER) pathway specifically, has heightened since these pathways have been shown to modulate important aspects of human disease. Modulation of the expression or activity of a particular BER enzyme, N-methylpurine DN...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Dixon, Monica, Woodrick, Jordan, Gupta, Suhani, Karmahapatra, Soumendra Krishna, Devito, Stephen, Vasudevan, Sona, Dakshanamurthy, Sivanesan, Adhikari, Sanjay, Yenugonda, Venkata M., Roy, Rabindra
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339462/
https://ncbi.nlm.nih.gov/pubmed/25650313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.12.067
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