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Discrimination of Lesion Removal of N-Methylpurine-DNA Glycosylase Revealed by a Potent Neutralizing Monoclonal Antibody
N-methylpurine-DNA glycosylase (MPG), a ubiquitous DNA repair enzyme, initiates excision repair of several N-alkylpurine adducts, induced by alkylating chemotherapeutics, and deaminated and lipid peroxidation-induced purine adducts. We have generated monoclonal antibodies (moAbs) against human MPG....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2702511/ https://ncbi.nlm.nih.gov/pubmed/17768096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.07.012 |
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