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Expression, purification and characterization of codon optimized human N-methylpurine-DNA glycosylase from Escherichia coli

N-methylpurine-DNA glycosylase (MPG), a ubiquitous DNA repair enzyme, initiates excision repair of several N-alkylpurine adducts, deaminated and lipid peroxidation-induced purine adducts. MPG from human and mouse has previously been cloned and expressed. However, due to the poor expression level in...

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Sonraí Bibleagrafaíochta
Main Authors: Adhikari, Sanjay, Manthena, Praveen Varma, Üren, Aykut, Roy, Rabindra
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702510/
https://ncbi.nlm.nih.gov/pubmed/18191412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2007.12.001
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