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Expression, purification and characterization of codon optimized human N-methylpurine-DNA glycosylase from Escherichia coli
N-methylpurine-DNA glycosylase (MPG), a ubiquitous DNA repair enzyme, initiates excision repair of several N-alkylpurine adducts, deaminated and lipid peroxidation-induced purine adducts. MPG from human and mouse has previously been cloned and expressed. However, due to the poor expression level in...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2702510/ https://ncbi.nlm.nih.gov/pubmed/18191412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2007.12.001 |
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