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Suppression of the HSF1-mediated proteotoxic stress response by the metabolic stress sensor AMPK

Numerous extrinsic and intrinsic insults trigger the HSF1-mediated proteotoxic stress response (PSR), an ancient transcriptional program that is essential to proteostasis and survival under such conditions. In contrast to its well-recognized mobilization by proteotoxic stress, little is known about...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Dai, Siyuan, Tang, Zijian, Cao, Junyue, Zhou, Wei, Li, Huawen, Sampson, Stephen, Dai, Chengkai
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4339117/
https://ncbi.nlm.nih.gov/pubmed/25425574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489062
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