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The heat-shock, or HSF1-mediated proteotoxic stress, response in cancer: from proteomic stability to oncogenesis
The heat-shock, or HSF1-mediated proteotoxic stress, response (HSR/HPSR) is characterized by induction of heat-shock proteins (HSPs). As molecular chaperones, HSPs facilitate the folding, assembly, transportation and degradation of other proteins. In mammals, heat shock factor 1 (HSF1) is the master...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Philos Trans R Soc Lond B Biol Sci |
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| Κύριος συγγραφέας: | |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The Royal Society
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5717525/ https://ncbi.nlm.nih.gov/pubmed/29203710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0525 |
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