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Heat shock proteins and cancer: intracellular chaperones or extracellular signalling ligands?
Heat shock proteins (HSPs) are found at elevated concentrations in tumour cells, and this increase reflects the proteotoxic stress experienced by the cells due to expanding levels of the mutated oncoproteins that drive tumorigenesis. The protection of oncogenic proteins by HSPs offers a window of vu...
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| 出版年: | Philos Trans R Soc Lond B Biol Sci |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Royal Society
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5717524/ https://ncbi.nlm.nih.gov/pubmed/29203709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0524 |
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