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Heat shock proteins and cancer: intracellular chaperones or extracellular signalling ligands?

Heat shock proteins (HSPs) are found at elevated concentrations in tumour cells, and this increase reflects the proteotoxic stress experienced by the cells due to expanding levels of the mutated oncoproteins that drive tumorigenesis. The protection of oncogenic proteins by HSPs offers a window of vu...

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書目詳細資料
發表在:Philos Trans R Soc Lond B Biol Sci
主要作者: Calderwood, Stuart K.
格式: Artigo
語言:Inglês
出版: The Royal Society 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717524/
https://ncbi.nlm.nih.gov/pubmed/29203709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0524
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