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Heat shock proteins and cancer: intracellular chaperones or extracellular signalling ligands?

Heat shock proteins (HSPs) are found at elevated concentrations in tumour cells, and this increase reflects the proteotoxic stress experienced by the cells due to expanding levels of the mutated oncoproteins that drive tumorigenesis. The protection of oncogenic proteins by HSPs offers a window of vu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Philos Trans R Soc Lond B Biol Sci
Päätekijä: Calderwood, Stuart K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Royal Society 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5717524/
https://ncbi.nlm.nih.gov/pubmed/29203709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0524
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