Leptin recruits Creb-regulated transcriptional coactivator 1 to improve hyperglycemia in insulin-deficient diabetes

OBJECTIVE: Leptin alleviates hyperglycemia in rodent models of Type 1 diabetes by activating leptin receptors within the central nervous system. Here we delineate whether non-canonical leptin signaling through the Creb-regulated transcriptional coactivator 1 (Crtc1) contributes to leptin-dependent i...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Kim, Geun Hyang, Szabo, Andras, King, Emily M., Ayala, Jennifer, Ayala, Julio E., Altarejos, Judith Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338314/
https://ncbi.nlm.nih.gov/pubmed/25737949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2014.12.006
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