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Changes in insulin sensitivity during leptin replacement therapy in leptin-deficient patients

Leptin replacement rescues the phenotype of morbid obesity and hypogonadism in leptin-deficient adults. However, leptin's effects on insulin resistance are not well understood. Our objective was to evaluate the effects of leptin on insulin resistance. Three leptin-deficient adults (male, 32 yr...

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Detalhes bibliográficos
Main Authors: Paz-Filho, Gilberto, Esposito, Karin, Hurwitz, Barry, Sharma, Anil, Dong, Chuanhui, Andreev, Victor, Delibasi, Tuncay, Erol, Halil, Ayala, Alejandro, Wong, Ma-Li, Licinio, Julio
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652497/
https://ncbi.nlm.nih.gov/pubmed/18854428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90450.2008
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