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Evolution of oligomeric state through allosteric pathways that mimic ligand binding
Evolution and design of protein complexes is almost always viewed through the lens of amino acid mutations at protein interfaces. We showed previously that residues not involved in the physical interaction between proteins make important contributions to oligomerisation by acting indirectly or allos...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4337988/ https://ncbi.nlm.nih.gov/pubmed/25525255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1254346 |
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