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Similarity in Shape Dictates Signature Intrinsic Dynamics Despite No Functional Conservation in TIM Barrel Enzymes

The conservation of the intrinsic dynamics of proteins emerges as we attempt to understand the relationship between sequence, structure and functional conservation. We characterise the conservation of such dynamics in a case where the structure is conserved but function differs greatly. The trioseph...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Tiwari, Sandhya P., Reuter, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807811/
https://ncbi.nlm.nih.gov/pubmed/27015412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004834
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