The H1-receptor antagonists terfenadine and loratadine inhibit spontaneous growth of neoplastic mast cells

OBJECTIVE: In mast cell (MC) neoplasms, clinical problems requiring therapy include i) the local aggressive and sometimes devastating growth of MC and ii) mediator-related symptoms. A key mediator of MC responsible for clinical symptoms is histamine. Therefore, the use of histamine receptor (HR) ant...

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Bibliografische gegevens
Gepubliceerd in:Exp Hematol
Hoofdauteurs: Hadzijusufovic, Emir, Peter, Barbara, Gleixner, Karoline V., Schuch, Karina, Pickl, Winfried F., Thaiwong, Tuddow, Yuzbasiyan-Gurkan, Vilma, Mirkina, Irina, Willmann, Michael, Valent, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337971/
https://ncbi.nlm.nih.gov/pubmed/20570632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2010.05.008
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