Growth-inhibitory effects of four tyrosine kinase inhibitors on neoplastic feline mast cells exhibiting a Kit exon 8 ITD mutation

Systemic mastocytosis (SM) in felines is a rare neoplasm defined by increased growth and accumulation of immature mast cells (MC) in various organs including the spleen. Although in many cases splenectomy is an effective approach, relapses may occur. In these patients, treatment options are limited....

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Detalhes bibliográficos
Publicado no:Vet Immunol Immunopathol
Main Authors: Hadzijusufovic, Emir, Peter, Barbara, Rebuzzi, Laura, Baumgartner, Christian, Gleixner, Karoline V., Gruze, Alexander, Thaiwong, Tuddow, Pickl, Winfried F., Yuzbasiyan-Gurkan, Vilma, Willmann, Michael, Valent, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763335/
https://ncbi.nlm.nih.gov/pubmed/19505729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vetimm.2009.05.007
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