A Single Phosphorodiamidate Morpholino Oligomer Targeting VP24 Protects Rhesus Monkeys against Lethal Ebola Virus Infection

Ebola viruses (EBOV) cause severe disease in humans and nonhuman primates with high mortality rates and continue to emerge in new geographic locations, including several countries in West Africa, the site of a large ongoing outbreak. Phosphorodiamidate morpholino oligomers (PMOs) are synthetic antis...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Warren, Travis K., Whitehouse, Chris A., Wells, Jay, Welch, Lisa, Heald, Alison E., Charleston, Jay S., Sazani, Pete, Reid, St. Patrick, Iversen, Patrick L., Bavari, Sina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
Assuntos:
Observation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337572/
https://ncbi.nlm.nih.gov/pubmed/25670780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02344-14
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