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Development of a Mouse-Adapted Live Attenuated Influenza Virus That Permits In Vivo Analysis of Enhancements to the Safety of Live Attenuated Influenza Virus Vaccine

The live attenuated influenza virus vaccine (LAIV) is preferentially recommended for use in persons 2 through 49 years of age but has not been approved for children under 2 or asthmatics due to safety concerns. Therefore, increasing safety is desirable. Here we describe a murine LAIV with reduced pa...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Cox, Andrew, Baker, Steven F., Nogales, Aitor, Martínez-Sobrido, Luis, Dewhurst, Stephen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337518/
https://ncbi.nlm.nih.gov/pubmed/25552727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02636-14
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