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Rare variant association studies: considerations, challenges and opportunities

Genome-wide association studies (GWASs) have successfully uncovered thousands of robust associations between common variants and complex traits and diseases. Despite these successes, much of the heritability of these traits remains unexplained. Because low-frequency and rare variants are not tagged...

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Dades bibliogràfiques
Publicat a:Genome Med
Autors principals: Auer, Paul L, Lettre, Guillaume
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337325/
https://ncbi.nlm.nih.gov/pubmed/25709717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0138-2
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