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Rare variant association studies: considerations, challenges and opportunities
Genome-wide association studies (GWASs) have successfully uncovered thousands of robust associations between common variants and complex traits and diseases. Despite these successes, much of the heritability of these traits remains unexplained. Because low-frequency and rare variants are not tagged...
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| Udgivet i: | Genome Med |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4337325/ https://ncbi.nlm.nih.gov/pubmed/25709717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0138-2 |
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