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The effect of phenotypic outliers and non-normality on rare-variant association testing

Rare-variant association studies (RVAS) have made important contributions to human complex trait genetics. These studies rely on specialized statistical methods for analyzing rare-variant associations, both individually and in aggregate. We investigated the impact that phenotypic outliers and non-no...

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Foilsithe in:Eur J Hum Genet
Main Authors: Auer, Paul L, Reiner, Alex P, Leal, Suzanne M
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970685/
https://ncbi.nlm.nih.gov/pubmed/26733287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2015.270
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