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Rare variant association studies: considerations, challenges and opportunities

Genome-wide association studies (GWASs) have successfully uncovered thousands of robust associations between common variants and complex traits and diseases. Despite these successes, much of the heritability of these traits remains unexplained. Because low-frequency and rare variants are not tagged...

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Bibliografski detalji
Izdano u:Genome Med
Glavni autori: Auer, Paul L, Lettre, Guillaume
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337325/
https://ncbi.nlm.nih.gov/pubmed/25709717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0138-2
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