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The Synthesis and Enzymatic Polymerization of Nucleotides Containing Mercury: Potential Tools for Nucleic Acid Sequencing and Structural Analysis

A simple acetoxymercuration reaction for introducing covalently bound mercury atoms into nucleotides is described. The 5-mercuriacetate derivatives of UTP, CTP, dUTP, and dCTP, as well as the 7-mercuriacetate derivative of 7-deazaATP, have been prepared by this procedure and tested as substrates for...

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Autors principals: Dale, R. M. K., Livingston, D. C., Ward, D. C.
Format: Artigo
Idioma:Inglês
Publicat: 1973
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC433709/
https://ncbi.nlm.nih.gov/pubmed/4365367
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