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Enzymatic Synthesis of Sequence-Defined Synthetic Nucleic Acid Polymers with Diverse Functional Groups
We describe the development and in-depth analysis of T4 DNA ligase-catalyzed DNA templated oligonucleotide polymerization toward the generation of diversely functionalized nucleic acid polymers. We demonstrate that the NNNNT codon set enables low codon bias, high fidelity, and high efficiency for th...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5330676/ https://ncbi.nlm.nih.gov/pubmed/27633832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201607538 |
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