Suppression of CYP2C9 by MicroRNA hsa-miR-128-3p in Human Liver Cells and Association with Hepatocellular Carcinoma

Published studies have identified genetic variants, somatic mutations, and changes in gene expression profiles that are associated with hepatocellular carcinoma (HCC), particularly involving genes that encode drug metabolizing enzymes (DMEs). CYP2C9, one of the most abundant and important DMEs, is i...

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Vydáno v:Sci Rep
Hlavní autoři: Yu, Dianke, Green, Bridgett, Marrone, April, Guo, Yongli, Kadlubar, Susan, Lin, Dongxin, Fuscoe, James, Pogribny, Igor, Ning, Baitang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336941/
https://ncbi.nlm.nih.gov/pubmed/25704921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08534
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