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Suppression of CYP2C9 by MicroRNA hsa-miR-128-3p in Human Liver Cells and Association with Hepatocellular Carcinoma

Published studies have identified genetic variants, somatic mutations, and changes in gene expression profiles that are associated with hepatocellular carcinoma (HCC), particularly involving genes that encode drug metabolizing enzymes (DMEs). CYP2C9, one of the most abundant and important DMEs, is i...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Yu, Dianke, Green, Bridgett, Marrone, April, Guo, Yongli, Kadlubar, Susan, Lin, Dongxin, Fuscoe, James, Pogribny, Igor, Ning, Baitang
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336941/
https://ncbi.nlm.nih.gov/pubmed/25704921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08534
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