The 40-residue insertion in Vibrio cholerae FadR facilitates binding of an additional fatty acyl-CoA ligand

FadR is a master regulator of fatty acid metabolism and influences virulence in certain members of Vibrionaceae. Among FadR homologs of the GntR family, the Vibrionaceae protein is unusual in that it contains a C-terminal 40-residue insertion. Here we report the structure of Vibrio cholerae FadR (Vc...

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Vydáno v:Nat Commun
Hlavní autoři: Shi, Wei, Kovacikova, Gabriela, Lin, Wei, Taylor, Ronald K., Skorupski, Karen, Kull, F. Jon
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4336772/
https://ncbi.nlm.nih.gov/pubmed/25607896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7032
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